Cerebral Extracellular Calcium Activity in Severe Hypoglycemia: Relation to Extracellular Potassium and Energy State
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چکیده
منابع مشابه
Extracellular calcium sensing and extracellular calcium signaling.
The cloning of a G protein-coupled extracellular Ca(2+) (Ca(o)(2+))-sensing receptor (CaR) has elucidated the molecular basis for many of the previously recognized effects of Ca(o)(2+) on tissues that maintain systemic Ca(o)(2+) homeostasis, especially parathyroid chief cells and several cells in the kidney. The availability of the cloned CaR enabled the development of DNA and antibody probes f...
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Outward current oscillations associated with transient membrane hyperpolarizations were induced in murine macrophage polykaryons by membrane depolarization in the absence of external Na+. Oscillations corresponded to a cyclic activation of Ca(2+)-dependent K+ currents (IKCa) probably correlated with variations in intracellular Ca2+ concentration. Addition of external Na+ (8 mM) immediately abol...
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The inotropic actions of isoproterenol in cat papillary muscles or trabeculae bathed in a salt solution containing 4 mM KCl were compared to those in similar muscles bathed in a salt solution containing 22 mM KCl. Although isoproterenol evoked the same increase in force of contraction in both groups of muscles, the time course of contraction differed markedly. In muscles bathed in 4 mM KCl, iso...
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Extracellular ion concentrations change as a function of neuronal activity and also represent important factors influencing the dynamic state of a population of neurons. In particular, relatively small changes in extracellular potassium concentration ( K+ o) mediate substantial changes in neuronal excitability and intrinsic firing patterns. While experimental approaches are limited in their abi...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 1984
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.1984.27